The dermal tolerance of Sterillium®, Sterillium® pure, Sterillium® Gel, Sterillium® Virugard® and Amphisept E was investigated. The study was randomised and double-blinded. The products were applied on intact skin for 6 days on 54 subjects, both atopics and non-atopics. All five alcohol-based hand disinfectants were well tolerated: no or only slight skin irritations occurred in comparison to water. There was no significant difference between non-atopics and atopics.