Clostridioides difficile-associated diarrhoea often connected to antibiotic therapy.
In healthy adults, Clostridioides difficile is a part of the normal intestinal flora in a small proportion. Treatment with antibiotics may lead to overgrowth of Clostridioides difficile, triggering diarrhoea. Symptoms very much depend on the type and quantity of toxins Clostridioides difficile produces. With the emergence of a new, hypervirulent ribotype 027 strain, there has been an increase of particularly severe cases.