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Motile cells that belong to the white blood cells (leucocytes) and have the task of identifying foreign bodies and eliminating microorganisms and tumour cells. Macrophages are produced in the bone marrow, appear in the blood as monocytes for several days and then spread from the blood to different tissues and organs such as the skin, lung, intestine and bones. When appearing there, they are also called Kupffer cells (liver), Langerhans cells (skin) and osteoclasts (bones).