Study

Effect of antiseptic irrigation on infection rates of traumatic soft tissue wounds: a longitudinal cohort study.

Study
Effect of antiseptic irrigation on infection rates of traumatic soft tissue wounds: a longitudinal cohort study.
from
Roth B, Neuenschwander R, Brill F, Wurmitzer F, Wegner C, Assadian O, Kramer A
Publication Year
2017
Published in
J Wound Care 26(3): 79-87
DOI
10.12968/jowc.2017.26.3.79
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Wound irrigation with PHMB prevented significantly more SSI compared with all other compounds used in this study.

In a retrospective, non-randomised, controlled longitudinal cohort study the preventive effect of different wound irrigation solutions on wound infection was investigated: Polyhexanide (PHMB), PVP iodine, hydrogen peroxide and Ringer's solution. Overall 4.2% of patients developed an SSI. The lowest percentage of SSIs occurred in the treatment group with wounds irrigated with PHMB (61 of 3,264 patients, 1.9 %), the most in wounds irrigated with hydrogen peroxide (75 of 643 patients, 11.7 %).

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