The Monkeypox virus (Orthopoxvirus simiae) is an enveloped virus of the Poxviridae family.
First symptoms of a monkeypox infection are flu-like: fever, headache, muscle aches and asthenia. As the disease progresses, typical skin lesions develop, often affecting the face and palms. However, other areas of the body, such as the urogenital area, can also be affected.
Monkeypox virus is mainly transmitted from animals to humans, e.g. through contact with secretions and excretions from infected animals. Rodents are the possible reservoir. However, transmission from human to human is also possible in the case of close contact with infected persons. This mainly includes contact with virus-containing material such as body fluids or skin crusts of infected persons.
Monkeypox infections occur mainly in West and Central Africa. Since the beginning of the 2000s, isolated infections with the virus have also been reported outside the African continent. In May 2022, increased cases of monkeypox were reported in North America and Europe, including Germany. Persons without a respective travel history (West and Central Africa) were also affected.
»Necessary spectrum of antimicrobial activity: